AZD3839 free base
Supplier | MedChemExpress |
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Product # | HY-13438-25 mg |
CAS # | 1227163-84-9 |
Pricing | 25 mg, USD $480.0 |
Biological Activity | AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease[1][2]. |
Purity | 99.99% |
MWt | 431.41 |
Formula | C₂₄H₁₆F₃N₅ |