Cardiotrophin-1, murine recombinant
CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.
| Supplier | CD BioSciences |
|---|---|
| Product # | APE-011 |
| Pricing | , Inquire |
| Product Category | Proteins/Enzymes |
| Gene ID | 13019 |
| Alternate Name | CT-1 |
| Molecular Weight | 21.3 kDa |
| Appearance | Lyophilized powder |
| Storage Conditions | -20°C |
| Gene Symbol | CT1 |
| Source | E. coli |
| Physical Form Description | Sterile filtered through a 0.2 micron filter. Lyophilized from 0.5 mg/mL in 5 mM Tris, pH 8.0 |
| Purity by SDS-PAGE | ≥98% |
| Amino Acid Sequence | SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEEYVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA AALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVETVLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LYGEWVSRTE GDLGQLVPGG VA |