MRK-016
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator that has nootropic properties. It has been found to produce rapid, ketamine-like antidepressant effects in animal models of depression.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1027 |
| CAS # | 783331-24-8 |
| Pricing | Customizable size, Inquiry |
| Synonym | MRK-016; MRK 016; MRK016. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C17H20N8O2 |
| Exact Mass | 368.1709 |
| Molecular Weight | 368.401 |
| Elemental Analysis | C, 55.43; H, 5.47; N, 30.42; O, 8.69 |
| IUPAC/Chemical Name | 3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)pyrazolo(1,5-d)(1,2,4)triazine |
| InChi Key | QYSYOGCIDRANAR-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C17H20N8O2/c1-10-6-11(23-27-10)15-21-19-7-12-14(17(2,3)4)16(22-25(12)15)26-8-13-18-9-20-24(13)5/h6-7,9H,8H2,1-5H3 |
| SMILES Code | CN1N=CN=C1COC2=NN3C(C4=NOC(C)=C4)=NN=CC3=C2C(C)(C)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |