LGK-974
LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7143 |
| Sku # | S7143-50mg |
| Pricing | 50mg, $970.00 |
Citations for this product:
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bioRxiv - Developmental Biology 2023Quote: ... or 0.02 µM LGK (Cat. # S7143, Selleck Chemicals). After an additional 24 h the cells were detached with Trypsin EDTA 0.25% (Cat# 25200056 ...
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bioRxiv - Genomics 2022Quote: HEK293Ts were grown in culture medium supplemented with 10 nM LGK (S7143, Selleck Chemicals) for the 48 hours preceding the seeding ...
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bioRxiv - Genomics 2022Quote: ... wild-type HEK293T cells were grown in culture medium supplemented with 10 nM LGK (S7143, Selleck Chemicals) for the 48 hours preceding the seeding ...
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bioRxiv - Genomics 2022Quote: ... 1 nM LGK (Cat. # S7143, Selleck Chemicals) or no stimulation ...
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bioRxiv - Genomics 2022Quote: ... β-catenin KO HEK293T cells were grown in culture medium supplemented with 10 nM LGK (S7143, Selleck Chemicals) for the 48 hours preceding the seeding ...