Recombinant Human Proinsulin protein
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
| Supplier | Creative Biomart |
|---|---|
| Product # | INS-315H |
| Pricing | 50ug : USD $319 |
| Product Category | Recombinant Protein |
| Shipping Country | USA |