N-Desmethylclozapine
Supplier | MedChemExpress |
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Product # | HY-G0021-10 mg |
CAS # | 6104-71-8 |
Pricing | 10 mg, USD $168.0 |
Synonyms | Norclozapine; Desmethylclozapine; Normethylclozapine |
MWt | 312.8 |
Formula | C₁₇H₁₇ClN₄ |
Biological Activity | N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist[1][2]. |
Purity | 99.72% |