Reverse transcriptase-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-130241 |
| CAS # | 2380001-43-2 |
| Pricing | inquire |
| Biological Activity | Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 IIIB, E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC50of 13.7 nM against HIV-1 reverse transcriptase enzyme[1]. |
| MWt | 447.45 |
| Formula | C₂₅H₁₇N₇O₂ |