Recombinant Human Anti-ZIKV NS1 Antibody Fab Fragment (AA12)
Provided is NS1-specific antibody found in an individual with symptomatic ZIKV infection. It was validated that antibody AA12 bound NS1 protein from both MR766 and PRVABC59 ZIKV. while NS1-specific mAbs do not neutralize virus in vitro, they can confer FcγR-mediated protection in vivo in a murine challenge model, which highlights the importance of NS1 epitopes in vaccine development.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-AP485-YC-F(E) |
| Pricing | Inquiry |
| Host | Human |
| Target | ZIKV NS1 |
| Species Reactivity | MR766, PRVABC59 |
| Type | Human Fab |
| Applications | ELISA, Flow Cytometry, Immunofluorescence, ADCC Assay, Function Assay |
| Storage | Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles |