Protease Activated Receptor 4 (PAR4) Antibody
Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis.It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults.Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration.The tumor suppressor WT1 represses and activates transcription.The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor.Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Supplier | Abbexa Ltd. |
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Product # | abx016047-100UL |
Pricing | 100 µl USD $420.5 |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Host | Mouse |
Tested Applications | ELISA, WB, IHC |
UniProt Primary AC | Q96IZ0 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |