APS-2-79 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100627A |
| CAS # | 2002381-31-7 |
| Pricing | inquire |
| Biological Activity | APS-2-79 hydrochloride is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling[1]. |
| MWt | 423.89 |
| Formula | C₂₃H₂₂ClN₃O₃ |