epsilon-V1-2, epsilon-PKC Inhibitor, Cys-conjugated

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Supplier Creative Peptides
Product # P75007
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MolecularWeight 947.1
Sequence
  • One Letter Code: EAVSLKPTC
  • Three Letter Code: H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-Cys-OH
Storage -20°C
Explanation This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein
Reference
  • 1. Johnson, J. et al. J. Biol. Chem. 271, 24962 (1996),
  • 2. Brandman, R. et al. J. Biol. Chem. 282, 4113 (2007).
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