C-C Motif Chemokine 5 (CCL5) Antibody
CCL5 Antibody is a Rabbit Polyclonal antibody against CCL5. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Supplier | Abbexa Ltd. |
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Product # | abx004305-50UL |
Pricing | 50 µl USD $319.0 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | WB |
UniProt Primary AC | P13501 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |