Cathepsin S inhibitor
Cathepsin S is expressed in antigen-presenting cells and plays a role in invariant chain processing and major histocompatibility complex class II (MHCII) antigen presentation leading to CD4+ T-cell activation. An oral Cathepsin S inhibitor that blocks MHCII antigen presentation could result in a T-cell-selective immunosuppressant agent with improved safety over the current standard of care for the treatment of rheumatoid arthritis, psoriasis, multiple sclerosis and other autoimmune-based inflammatory diseases.
Supplier | BOC Sciences |
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Product # | B0084-463202 |
Pricing | 10 mg/unit USD $199 |
Cas | 1373215-15-6 |
Molecular Weight | 484.52 |
Molecular Formula | C25H29FN4O5 |
Canonical SMILES | CNC(=O)OC1COC2=C(C1NC(=O)C3=CC=C(C=C3)F)C=C(C=C2)N4CCN(CC4)C5COC5 |