α-Synuclein (67-78) (human)
The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity.
Supplier | BOC Sciences |
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Product # | BAT-014851 |
Pricing | Inquire |
Cas | 2243206-99-5 |
Molecular Weight | 1001.14 |
Molecular Formula | C43H76N12O15 |