α-Synuclein (67-78) (human)

The Parkinson's disease-associated protein α-synuclein (α-syn) is not only expressed in the cytoplasm of neurons, but also secreted in the extracellular space and internalized into glial cells through a lipid raft dependent process. The tilted peptide α-synuclein(67-78) has a high affinity with cholesterol and is toxic to cultured astrocytes. The glycosphingolipid-binding domain of alpha-synuclein (34-45) encapsulates a cholesterol-recognition consensus motif with a low affinity and no toxicity.
Supplier BOC Sciences
Product # BAT-014851
Pricing Inquire
Cas 2243206-99-5
Molecular Weight 1001.14
Molecular Formula C43H76N12O15
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