ZLJ-6
ZLJ-6 is a dual inhibitor of COX and 5-lipoxygenase (5-LO) with IC50 values of 0.73, 0.31, and 0.99 μM for COX-1, COX-2, and 5-LO, respectively. It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers, a common side effect of non-selective COX inhibitors.
| Supplier | BOC Sciences |
|---|---|
| Product # | 1051931-39-5 |
| Pricing | Inquire |
| Cas | 1051931-39-5 |
| Molecular Weight | 375.4 |
| Molecular Formula | C12H13N3O3S·CH3SO3H |
| Canonical SMILES | CN1C(=CC2=CC=C(C=C2)S(=O)(=O)C)C(=O)N=C1N.CS(=O)(=O)O |