iCRT-14-[d5]
A labelled potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between β-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
| Supplier | BOC Sciences |
|---|---|
| Product # | BLP-019868 |
| Pricing | Inquire |
| Cas | 1795144-12-5 |
| Molecular Weight | 380.47 |
| Molecular Formula | C21H12D5N3O2S |