MPEP HCl
MPEP is a selective mGluR5 antagonist. MPEP reverses maze learning and PSD-95 deficits in Fmr1 knock-out mice. MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: significance for the use as anxiolytic/antidepressant drug.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD308 |
| CAS # | 219911-35-0 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | MPEP; MPEP HCl; MPEP hydrochloride. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C14H12ClN |
| Molecular Weight | 229.707 |
| Elemental Analysis | C, 73.20; H, 5.27; Cl, 15.43; N, 6.10 |
| IUPAC/Chemical Name | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| InChi Key | PKDHDJBNEKXCBI-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C14H11N.ClH/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13;/h2-9H,1H3;1H |
| SMILES Code | CC1=NC(C#CC2=CC=CC=C2)=CC=C1.[H]Cl |
| Appearance | Yellow solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |