Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20)
Recombinant Human Antibody (HK20) is capable of binding to HIV-1 gp41, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 gp41 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 gp41 mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. HK20 IgG have limited neutralization breadth and potency while smaller HK20 Fabs and scFv reveal a broad cross clade neutralization breadth.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABC-069 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 gp41 |
| Species Reactivity | HIV-1 |
| Type | Human IgG |
| Applications | WB, ELISA, Neut |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |