Actinin Alpha 2 (ACTN2) Antibody

ACTN2 Antibody is a Rabbit Polyclonal antibody against ACTN2. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

• Supplier: Abbexa Ltd.
• Product #: abx002676-20UL
• Clonality: Polyclonal
• Conjugation: Unconjugated
• Host: Rabbit
• Tested Applications: WB, IHC, IF/ICC
• UniProt Primary AC: P35609
• Dry Ice: No
• Availability: Shipped within 5-10 working days.
• Note: This product is for research use only.