Afuco™ Anti-Human Hla ADCC Therapeutic Antibody (MEDI4893), ADCC Enhanced
Anti-Hla ADCC Enhanced Antibody (MEDI4893) is an ADCC enhanced antibody produced by our Afuco™ platform. MEDI4893 is a neutralizing human monoclonal antibody that targets α-toxin (AT) and is currently undergoing evaluation in the field of Staphylococcus aureus-mediated diseases. In particular, MEDI4893 not only sterically blocks binding of AT to its cell receptor but also prevents it from adopting a lytic heptameric trans-membrane conformation.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-343CL |
| Pricing | Inquiry |
| Host | Human |
| Target | Hla |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C |