Tulrampator
Tulrampator, also known as S-47445 and CX-1632, is a positive allosteric modulator (PAM) of the AMPA receptor (AMPAR), an ionotropic glutamate receptor, which is under development by RespireRx Pharmaceuticals (formerly Cortex Pharmaceuticals) and Servier for the treatment of major depressive disorder (as an adjunct), Alzheimer's disease, dementia, and mild cognitive impairment.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1214 |
| CAS # | 1038984-31-4 |
| Pricing | Customizable size, Inquiry |
| Synonym | Tulrampator; S-47445; S 47445; S47445; CX-1632; CX 1632; CX1632; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C20H17FN4O3 |
| Exact Mass | 380.1285 |
| Molecular Weight | 380.3794 |
| Elemental Analysis | C, 63.15; H, 4.50; F, 4.99; N, 14.73; O, 12.62 |
| IUPAC/Chemical Name | 8-cyclopropyl-3-[2-(3-fluorophenyl)ethyl]-7,8-dihydro-3H-[1,3]oxazino[6,5-g][1,2,3]benzotriazine-4,9-dione |
| InChi Key | JHCFQXNWYDLBOG-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C20H17FN4O3/c21-13-3-1-2-12(8-13)6-7-25-20(27)15-10-18-16(9-17(15)22-23-25)19(26)24(11-28-18)14-4-5-14/h1-3,8-10,14H,4-7,11H2 |
| SMILES Code | O=C1N(CCC2=CC=CC(F)=C2)N=NC3=CC4=C(OCN(C5CC5)C4=O)C=C13 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |