Anti-Human CD40 ligand Therapeutic Antibody (Toralizumab)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD40 ligand. Toralizumab was a humanized monoclonal antibody and an immunosuppressive drug. Possible indications included treatment of antibody-mediated disorders (immune thrombocytopenic purpura, lupus nephritis, rheumatoid arthritis), T-cell-mediated diseases (multiple sclerosis, Crohn's disease, and transplantations such as solid organ transplantation, pancreatic islet cell transplantation, and corneal transplantation), and B-cell malignancies such as CLL/small lymphocytic lymphoma, follicular cell lymphoma grade I or II, marginal zone lymphoma, mantle cell lymphoma, MALT lymphoma, Waldenstrom's macroglobulinemia, monocytoid B-cell lymphoma; relapsed/refractory Hodgkin's disease).
| Supplier | Creative Biolabs |
|---|---|
| Product # | TAB-876 |
| Pricing | Inquiry |
| Host | Mouse |
| Target | CD40 ligand |
| Species Reactivity | Human |
| Type | IgG1 - kappa |
| Applications | Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods. |
| Storage | Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles. |