DAPT
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13027-10 mg |
| CAS # | 208255-80-5 |
| Pricing | 10 mg, USD $115.0 |
| Synonyms | GSI-IX |
| MWt | 432.46 |
| Formula | C₂₃H₂₆F₂N₂O₄ |
| Biological Activity | DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment[1][2]. |
| Purity | 99.93% |