Palmitic Acid

Palmitic acid occurs as white crystalline scales with a slight characteristic odor and taste.
Supplier CD Formulation
Product # PE0408
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product1 Excipients for Liquid Dosage Form
Molecular Formula C16H32O2
Molecular Weight 256.42
Applications Palmitic acid is used in oral and topical pharmaceutical formulations. Palmitic acid has been used in implants for sustained release of insulin in rats.
Safety Palmitic acid is used in oral and topical pharmaceutical formulations and is generally regarded as nontoxic and nonirritant at the levels employed as an excipient. However, palmitic acid is reported to be an eye and skin irritant at high levels and is poisonous by intravenous administration. LD50 (mouse, IV): 57 mg/kg
Incompatibilities Palmitic acid is incompatible with strong oxidizing agents and bases.
Synonyms Acidum palmiticum; cetylic acid; Edenor C16 98-100; Emersol 140; Emersol 143; n-hexadecoic acid; hexadecylic acid; Hydrofol; Hystrene 9016; Industrene 4516; Lunac P-95; NAA-160; 1-pentadecanecarboxylic acid
CAS Number 57-10-3
Category Emulsifying Agents; Skin Penetrant; Tablet and Capsule Lubricant
UNII 2V16EO95H1
Chemical Name Hexadecanoic acid
Grade Pharmceutical Excipients
Administration route Oral
Dosage Form Oral tablets
Stability and Storage Conditions The bulk material should be stored in a well-closed container in a cool, dry, place.
Source and Preparation Palmitic acid occurs naturally in all animal fats as the glyceride, palmitin, and in palm oil partly as the glyceride and partly uncombined. Palmitic acid is most conveniently obtained from olive oil after removal of oleic acid, or from Japanese beeswax. Synthetically, palmitic acid may be prepared by heating cetyl alcohol with soda lime to 270℃ or by fusing oleic acid with potassium hydrate.
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