CMP-5 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-113846 |
| CAS # | 1030021-40-9 |
| Pricing | inquire |
| Biological Activity | CMP-5 hydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 hydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 hydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected[1][2]. |
| MWt | 351.87 |
| Formula | C₂₁H₂₂ClN₃ |