Human Anti-HIV-1 Env Recombinant Antibody (clone PGT151)
Recombinant Human Antibody (PGT151) is capable of binding to HIV-1 env, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 env mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 env mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The PGT151 epitope is comprised of residues and glycans at the interface of gp41 and gp120 within a single protomer and glycans from both subunits of a second protomer and represents a neutralizing epitope that is dependent on both gp120 and gp41.
| Supplier | Creative Biolabs |
|---|---|
| Product # | PABL-153 |
| Pricing | Inquiry |
| Host | Human |
| Target | HIV-1 Env |
| Species Reactivity | HIV-1 |
| Type | Human IgG |
| Applications | WB, ELISA, FuncS |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |