Supplier |
CD Formulation |
Product # |
PE-0623 |
Pricing |
, Inquire for price
|
product1 |
Excipients for Liquid Dosage Form
|
Molecular Formula |
C18H35NO
|
Molecular Weight |
281.48
|
Applications |
Azone, as an efficient skin penetration enhancer and a new type of non-ionic surfactant, has been widely applied in the fields of medicine, daily chemical, pesticide, printing and dyeing, chemical fiber, leather and so on.
|
Safety |
When the concentration is less than 50%, it has no irritation to the skin. It is a non-toxic, safe and efficient transdermal absorption promoter.
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Incompatibilities |
Incompatibility with strong acid drugs, vaseline, etc.
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CAS Number |
59227-89-3
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Category |
Surfactant
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Chemical Name |
1-dodecyl azocyclic heptanone 2-ketone
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Grade |
Pharmceutical Excipients
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Administration route |
Administration by injection, oral administration, percutaneous administration, vaginal administration
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Dosage Form |
injection, oral, percutaneous , vaginal preparations
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Stability and Storage Conditions |
It is stable to heat, but not to acid and base. Other functional components in the formula may separate oil from water.
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Source and Preparation |
It is prepared by the reaction of bromododecane with caprolactam in the presence of strong bases such as metallic sodium and sodium hydroxide, or in the condition of phase transfer catalysis of quaternary ammonium salts.
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