| Supplier |
Creative Peptides |
| Product # |
10-101-20 |
| CAS # |
145781-92-6 |
| Pricing |
Inquire
|
| Synonyms |
(D-Ser(tBu)6; Azagly10)-LHRH; goserelin; Zoladex; Decapeptide I; Goserelin acetate; Gosereline; Goserelinum; Goserelina; Goserelin; ICI 118630; ICI-118630; ICI118630
|
| MolecularFormula |
C59H84N18O14
|
| MolecularWeight |
1269.43
|
| Source |
Synthetic
|
| Sequence |
Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Azagly-NH2 acetate salt
|
| Explanation |
Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production.
|
| Application |
Goserelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
|
| AreasOfInterest |
Cancer Research, Pituitary & Hypothalamic Hormones, Veterinary Medicine
|
| LongTermStorageConditions |
−20°C
|