Benzomalvin A
It is produced by the strain of Penicillum sp. Benzomalvin A was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro with IC50 of 383.2 μM. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively).
| Supplier | BOC Sciences |
|---|---|
| Product # | 157047-96-6 |
| Pricing | Inquire |
| Cas | 157047-96-6 |
| Molecular Weight | 381.43 |
| Molecular Formula | C24H19N3O2 |
| Canonical SMILES | CN1C(C2=NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4C1=O)CC5=CC=CC=C5 |