Gamma-Glutamylcysteine Synthetase (GCLC) Antibody
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Supplier | Abbexa Ltd. |
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Product # | abx030331-80UL |
Pricing | 80 µl USD $326.25 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Host | Rabbit |
Tested Applications | ELISA, WB |
UniProt Primary AC | P48506 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |