Ro 32-0432 hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-108601A-1 mg |
| CAS # | 1781828-85-0 |
| Pricing | 1 mg, USD $360.0 |
| Biological Activity | Ro 32-0432 hydrochloride is a potent, selective, ATP-competitive and orally active PKC inhibitor. The IC50 values of Ro 32-0432 hydrochloride for PKCα, PKCβI, PKCβII, PKCγ and PKCε are 9.3 nM, 28 nM, 30 nM, 36.5 nM and 108.3 nM, respectively. Ro 32-0432 hydrochloride is also a selective G protein-coupled receptor kinase 5 (GRK5) inhibitor. Ro 32-0432 hydrochloride prevents T-cell activation and has the potential for chronic inflammatory and autoimmune diseases research[1][2]. |
| MWt | 489.01 |
| Formula | C₂₈H₂₉ClN₄O₂ |