Paroxetine Hydrochloride
Paroxetine is a potent and one of the most specific selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitors (SSRIs).It acts by binding to ST (serotonin transporter/SERT) with high affinity. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex thereby blocking reuptake of serotonin by the pre-synaptic transporter. Paroxetine HCl has also displayed a high affinity for muscarinic acetylcholine receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1116 |
| CAS # | 78246-49-8 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Paroxetine Hydrochloride; Paroxetine Hcl; Paroxat; Aropax 20; (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride; Paxil; Seroxat; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H21ClFNO3 |
| Molecular Weight | 365.8294 |
| Elemental Analysis | C, 62.38; H, 5.79; Cl, 9.69; F, 5.19; N, 3.83; O, 13.12 |
| IUPAC/Chemical Name | (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;hydrochloride |
| InChi Key | GELRVIPPMNMYGS-RVXRQPKJSA-N |
| InChi Code | InChI=1S/C19H20FNO3.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;/h1-6,9,14,17,21H,7-8,10-12H2;1H/t14-,17-;/m0./s1 |
| SMILES Code | C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |