O-Demethyl-Gefitinib

O-Desmethyl gefitinib, a major active metabolite of gefitinib, is a potent EGFR (ErbB1/HER1) inhibitor, inhibits subcellular EGFR tyrosine kinase through a mechanism similar to that of gefitinib with IC50 values of 36 and 22 nM, respectively.

• Supplier: Selleck Chemicals
• Product #: E0833
• Sku #: E0833-5mg