Brevilin A
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N2959-10 mg |
| CAS # | 16503-32-5 |
| Pricing | 10 mg, USD $430.0 |
| Biological Activity | Brevilin A is a sesquiterpene lactone isolated from Centipeda minima with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 µM) in Cancer Cells. Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K/AKT/mTOR inactivation in colon adenocarcinoma cell CT26[1][2]. |
| Purity | ≥99.0% |
| MWt | 346.42 |
| Formula | C₂₀H₂₆O₅ |