BACE-1 Inhibitor
BACE-1 Inhibitor is a potent, selective and cell-permeable inhibitor of human β-secretase (BACE-1) binding to the active site of BACE-1. It inhibits secretion of amyloid-β (Aβ) precursor protein (APP; IC50 = 29 nM) in HEK293T cells and also suppresses formation of the Aβ peptides Aβ38, Aβ40, and Aβ42 in primary chick neurons (IC50s = 3.7, 4.7, and 4.8 nM, respectively).
| Supplier | BOC Sciences |
|---|---|
| Product # | 797035-11-1 |
| Pricing | Inquire |
| Cas | 797035-11-1 |
| Molecular Weight | 578.72 |
| Molecular Formula | C31H38N4O5S |
| Canonical SMILES | CC(C1=CC=CC=C1)NC(=O)C2=CC(=CC(=C2)N(C)S(=O)(=O)C)C(=O)NC(CC3=CC=CC=C3)C(CNC4CC4)O |