6-Aminonicotinamide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-W010342-10 mM * 1 mL |
| CAS # | 329-89-5 |
| Pricing | 10 mM * 1 mL, USD $55.0 |
| Biological Activity | 6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as Cisplatin, in killing cancer cells[1][2][3][4]. |
| MWt | 137.14 |
| Formula | C₆H₇N₃O |