| Supplier |
CD BioSciences |
| Product # |
AMA-0534 |
| Pricing |
100 µL, Inquire
|
| Product Category |
Antibodies
|
| Application |
WB, IP
|
| Product Usage Information Dilution |
Western Blotting (1:1000); Immunoprecipitation (1:50)
|
| Reactivity |
Human, Mouse, Rat
|
| Host |
Rabbit
|
| Gene ID |
1033
|
| UniProt ID |
|
| Source/Isotype |
Rabbit IgG
|
| MW (Target) |
23 kDa
|
| Storage |
Store at -20°C. Do not aliquot the antibody.
|
| Purification |
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro107 of human CDKN3 protein.
|
| Background |
CDKN3 (Cyclin-Dependent Kinase Inhibitor 3)/KAP (Kinase-Associated Phosphatase) is a dual specificity phosphatase that regulates cell cycle progression through dephosphorylation and inhibition of cyclin-dependent kinases CDKN3 promotes cancer cell proliferation and invasion as well as resistance to cisplatin Overexpression of CDKN3 is associated with tumor progression and poor prognosis in several human cancers.
|