Afuco™ Anti-Human SLC40A1 ADCC Therapeutic Antibody (LY2928057), ADCC Enhanced
Anti-SLC40A1 ADCC Enhanced Antibody (LY2928057) is an ADCC enhanced antibody produced by our Afuco™ platform. LY2928057 is a novel humanized IgG4 monoclonal antibody that binds to human ferroportin with a high affinity, blocks the binding of human hepcidin to ferroportin, and is a potent inhibitor of hepcidin activity in a recombinant ferroportin expressing HEK 293 cell-based assay. LY2928057 may provide therapeutic benefit for patients with hepcidin-related anemia by stabilizing ferroportin located on the cell surface, thus restoring iron export and erythropoiesis. LY2928057 is currently in clinical evaluation.
| Supplier | Creative Biolabs |
|---|---|
| Product # | AFC-554CL |
| Pricing | Inquiry |
| Host | Humanized |
| Target | SLC40A1 |
| Species Reactivity | Human |
| Type | ADCC enhanced antibody |
| Storage | Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles. |