Caspase 3 (CASP3) Antibody

CASP3 Antibody is a Rabbit Polyclonal antibody against CASP3. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Supplier Abbexa Ltd.
Product # abx001768-200UL
Pricing 200 µl USD $717.75
Clonality Polyclonal
Conjugation Unconjugated
Host Rabbit
Tested Applications WB, IHC, IF/ICC
UniProt Primary AC P42574
Dry Ice No
Availability Shipped within 5-10 working days.
Note This product is for research use only.
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