Microcrystalline Cellulose PH301
Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is commercially available in different particle sizes and moisture grades that have different properties and applications.
Supplier | CD Formulation |
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Product # | PE0375 |
Pricing | , Inquire for price |
product1 | Suspending Agents |
Molecular Formula | (C6H10O5)n n n≈220 |
Molecular Weight | ≈36000 |
Applications | Adsorbent; suspending agent; diluent for tablets and capsules; disintegrant for tablets. Microcrystalline cellulose PH301.is suitable for wet granulation. |
Safety | This product is widely used in oral pharmaceutical preparations and food, and is a relatively non-toxic and non-irritating substance. This product is not absorbed after oral administration and has almost no potential toxicity. A large amount of use may cause mild diarrhea, and it is not difficult to use as a pharmaceutical excipient. Abuse of certain tablets containing cellulose, such as inhalation or injection administration, can lead to fibrous granulomas. |
Incompatibilities | This product is incompatible with strong oxidizing agents. |
Synonyms | Avicel PH 301; Celex PH301; cellulose-gel PH301; Celphere PH301; Ceolus-KG PH301; crystalline-cellulose PH301; E460 PH301; Emcocel PH301; Ethispheres PH301; Fibrocel PH301; Pharmacel PH301; Tabulose PH301; Vivapur PH301 |
CAS Number | 9004-34-6 |
Category | Adsorbent; Suspending Agents; Diluent for tablets and capsules; Disintegrant for tablets |
UNII | OP1R32D61U |
Chemical Name | Cellulose PH301 |
Grade | Pharmceutical Excipients |
Administration route | Oral; Topical |
Dosage Form | Inhalation; Oral Capsule; Granules; Suspension; Syrup; Tablet; Topical and Vaginal |
Stability and Storage Conditions | This product is a hygroscopic, but stable substance. Large quantities of storage must be placed in airtight containers in a cool and dry environment. |
Source and Preparation | Microcrystalline cellulose can be obtained by controlled hydrolysis of α-cellulose with dilute mineral acid solution, and α-cellulose can be obtained from fiber pulp of cellulose-containing plants. After hydrolysis, the hydrolyzed cellulose is filtered and purified, and the water slurry is spray-dried to form dry porous particles with a wide particle size distribution. |