5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite

5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a 5-methylcytosine base modified with a benzoyl (Bz) group. Additionally, it features a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for applications such as gene synthesis, RNA interference, and nucleic acid probe development in molecular biology research.

• Supplier: BOC Sciences
• Product #: BRP-00408
• Molecular Weight: 975.12
• Molecular Formula: C52H55N4O9PS2
• Canonical SMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC