TP0473292
TP0473292 is an adamantane carboxylic acid ester prodrug of TP0178894, a metabotropic glutamate 2 and 3 receptor antagonist for use as an antidepressant. TP0473292 has undergone phase 1 clinical trials for treatment of depression.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1236 |
| CAS # | N/A |
| Pricing | Customizable size, Inquiry |
| Synonym | TP0473292; TP 0473292; TP-0473292 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C28H33F2NO7 |
| Exact Mass | 533.2225 |
| Molecular Weight | 533.57 |
| Elemental Analysis | C, 63.03; H, 6.23; F, 7.12; N, 2.63; O, 20.99 |
| IUPAC/Chemical Name | (1R,2R,3R,5R,6R)-2-(((S)-1-((adamantane-1-carbonyl)oxy)ethoxy)carbonyl)-2-amino-6-fluoro-3-((4-fluorobenzyl)oxy)bicyclo[3.1.0]hexane-6-carboxylic acid |
| InChi Key | OCKJWSRXCCMMEI-AHGQKZNCSA-N |
| InChi Code | InChI=1S/C28H33F2NO7/c1-14(37-24(34)26-10-16-6-17(11-26)8-18(7-16)12-26)38-25(35)28(31)21(9-20-22(28)27(20,30)23(32)33)36-13-15-2-4-19(29)5-3-15/h2-5,14,16-18,20-22H,6-13,31H2,1H3,(H,32,33)/t14-,16?,17?,18?,20+,21+,22-,26?,27+,28-/m0/s1 |
| SMILES Code | O=C([C@@]1(F)[C@]2([H])C[C@@H](OCC3=CC=C(F)C=C3)[C@@](N)(C(O[C@H](OC(C45CC6CC(C5)CC(C6)C4)=O)C)=O)[C@]12[H])O |
| Appearance | To be determined |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | To be determined |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | To be determined |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |