| Supplier |
Creative Peptides |
| Product # |
X21164 |
| Pricing |
Inquire
|
| MolecularWeight |
1100.2
|
| Sequence |
- One Letter Code: Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2
- Three Letter Code: Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(Dnp)-NH2
|
| Storage |
-20°C
|
| Explanation |
This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.
|
| Reference |
- 1. Lauer-Fields, JL. and GB. Fields, Biol. Chem. 383, 1095 (2002);
- 2. Lauer-Fields, JL. et al. Biochem. 40, 5795 (2001);
- 3. Knauper, V. et al. J. Biol. Chem. 271, 1544 (1996).
|