Taltobulin hydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-15584B-10 mg |
| Pricing | 10 mg, USD $240.0 |
| Synonyms | HTI-286 hydrochloride; SPA-110 hydrochloride |
| MWt | 510.11 |
| Formula | C₂₇H₄₄ClN₃O₄ |
| Biological Activity | Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin hydrochloride inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1]. |
| Purity | 98.34% |