| Supplier |
Creative Peptides |
| Product # |
R1804 |
| CAS # |
1659305-78-8 |
| Pricing |
Inquire
|
| MolecularFormula |
C93H144ClN23O21S2
|
| MolecularWeight |
2019.86
|
| Sequence |
- One Letter Code: Ac-VP-{Phe(3-Cl)}-{Hcy}-LRK-{Nle}-PASFCKPPE-NH2 (Disulfide bridge:Hcy4-Cys13)
- Three Letter Code: Ac-{Val}{Pro}{Phe(3-Cl)}{Hcy}{Leu}{Arg}{Lys}{Nle}{Pro}{Ala}{Ser}{Phe}{Cys}{Lys}{Pro}{Pro}{Glu}-NH2 (Disulfide bridge:Hcy4-Cys13)
|
| Storage |
Desiccate at -20°C
|
| ShippingCondition |
Room temperature in continental US; may vary elsewhere.
|
| Explanation |
YAP-TEAD-IN-1 is a potent and competitive inhibitor of YAP–TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd=40 nM).
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