tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase

The enzyme, which is a member of the S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes superfamily, binds two [4Fe-4S] clusters as well as the transferred sulfur. The sulfur donor is believed to be one of the [4Fe-4S] clusters, which is sacrificed in the process, so that in vitro the reaction is a single turnover. The identity of the electron donor is not known.

• Supplier: Creative Enzymes
• Product #: EXWM-3431