LY-404187
LY-404187 is an ampakine, AMPA receptor potentiator. LY-404187 has been demonstrated to enhance cognitive function in animal studies, and has also shown effects suggesting antidepressant action as well as having possible application in the treatment of schizophrenia, Parkinson's disease and ADHD. These effects appear to be mediated through multiple mechanisms of action secondary to AMPA receptor potentiation, with a prominent effect seen in research being increased levels of BDNF in the brain.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1630 |
| CAS # | 211311-95-4 |
| Pricing | Customizable size, Inquiry |
| Synonym | LY-404187; LY 404187; LY404187. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H22N2O2S |
| Exact Mass | 342.1402 |
| Molecular Weight | 342.457 |
| Elemental Analysis | C, 66.64; H, 6.48; N, 8.18; O, 9.34; S, 9.36 |
| IUPAC/Chemical Name | 2-Propanesulfonamide, N-(2-(4'-cyano(1,1'-biphenyl)-4-yl)propyl)- |
| InChi Key | HOQAVGZLYRYHSO-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H22N2O2S/c1-14(2)24(22,23)21-13-15(3)17-8-10-19(11-9-17)18-6-4-16(12-20)5-7-18/h4-11,14-15,21H,13H2,1-3H3 |
| SMILES Code | CC(S(=O)(NCC(C1=CC=C(C2=CC=C(C#N)C=C2)C=C1)C)=O)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |