DLK-IN-1
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-114331-10 mM * 1 mL |
| CAS # | 1620574-24-4 |
| Pricing | 10 mM * 1 mL, USD $605.0 |
| Biological Activity | DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimer’s Disease. |
| Purity | 99.47% |
| MWt | 423.43 |
| Formula | C₂₀H₂₄F₃N₅O₂ |