Camelid Anti-B. anthracis PA83 Recombinant Single Domain Antibody (clone JKH-C7)
This product is a recombinant Camelid single domain antibody that recognizes B. anthracis PA83. This antibody inhibits conversion of the PA oligomer from "pre-pore" to its SDS and heat-resistant "pore" conformation while not preventing cleavage of full-length 83-kDa PA (PA83) by cell surface proteases to its oligomer-competent 63-kDa form (PA63). The antibody prevents endocytosis of the cell surface-generated PA63 subunit but not preformed PA63 oligomers formed in solution.
| Supplier | Creative Biolabs |
|---|---|
| Product # | HPAB-0655-YJ-VHH |
| Pricing | Inquiry |
| Host | Camelid |
| Target | B. anthracis PA83 |
| Species Reactivity | B. anthracis |
| Type | Camelid VHH |
| Applications | ELISA, Neut |
| Storage | Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles. |