Donepezil HCl
Donepezil HCl is a GSK3 and AChE inhibitor and potential σ1 receptor agonist used to treat Alzheimer's disease. It also improves learning and memory, downregulates expression of NR1 subuinit of NMDA receptors, decreases left ventricular end diastolic pressure, and increases left ventricular contractility.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1505 |
| CAS # | 120011-70-3 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Aricept; E-2020; E2020; E 2020; Donepezil HCl |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C24H30ClNO3 |
| Molecular Weight | 415.95 |
| Elemental Analysis | C, 69.30; H, 7.27; Cl, 8.52; N, 3.37; O, 11.54 |
| IUPAC/Chemical Name | 2-((1-benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride |
| InChi Key | XWAIAVWHZJNZQQ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H |
| SMILES Code | O=C1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2933.39.9100 |
| Availability | 2 Weeks |